PUBLICATIONS

 

 

 

Banales JM, Iñarrairaegui M, Arbelaiz A, Milkiewicz P, Muntane J, Muñoz-Bellvis L, La Casta A, Gonzalez LM, Arretxe E, Alonso C, Martínez-Arranz I, Lapitz A, Santos-Laso A, Avila MA, Martínez-Chantar ML, Bujanda L, Marin JJG, Sangro B, Macias RIR. Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis. Hepatology 2019 Aug;70(2):547-562 .

Rovira-Llopis S, Apostolova N, Bañuls C, Muntané J, Rocha M, Victor VM. Mitochondria, the NLRP3 inflammasome and sirtuins in type 2 diabetes: new therapeutic targets. Antioxid Redox Signal 2018 Sep 10;29(8):749-791.

Rada P, Pardo V, Mobasher M, Garcia I, Ruiz L, Gonzalez Rodriguez A, Sánchez Ramos C, Muntané J, Alemany S, James LP, Simpson KJ, Monsalve M, Valdecantos MP, Valverde A. Sirt1 controls acetaminophen hepatotoxicity by modulating inflammation and oxidative stress. Antioxid Redox Signal 2018 May 1;28(13):1187-1208.

Rodríguez-Hernández MA, González R, De la Rosa AJ, Gallego P, Ordoñez R, Navarro-Villarán E, Contreras L, Rodríguez-Arribas M, González-Gallego J, Álamo-Martínez JM, Marín-Gómez LM, Del Campo JA, Quiles JL, Fuentes JM, de la Cruz J, Mauriz JL, Padillo FJ, Muntané J. Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells. J Cell Physiol 2018 Jan;234(1):692-708. 

Macias RIR, Banales JM, Sangro B, Muntané J, Avila MA, Lozano E, Perugorria MJ, Padillo FJ, Bujanda L, Marin JJG. The search for novel diagnotic and prognostic biomarkers in cholangiocarcinoma. Biochim Biophys Acta MBD 2018 Apr;1864(4 Pt B):1468-1477.

Del Campo JA, García-Valdecasas M, Gil-Gómez A, Rojas Á, Gallego P, Ampuero J, Gallego-Durán R, Pastor H, Grande L, Padillo FJ, Muntané J, Romero-Gómez M. Simvastin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy. PLoS One. 2018 Jan 31;13(1):e0191805.

Pavillard LE, Cañadas-Lozano D, Alcocer-Gómez E, Marín-Aguilar F, Pereira S, Robertson AAB, Muntané J, Ryffel B, Cooper MA, Quiles JL, Bullón P, Ruiz-Cabello J, Cordero MD. NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction. Oncotarget. 2017 Sep 8;8(59):99740-99756.

González R, Molina-Ruiz FJ, Ruiz JAB, Padilla CA, Muntané J.  Regulation of cell survival, apoptosis and epithelial to mesenchymal transition by nitric oxide-dependent post-translational modifications. Antioxid. Redox Signal. 2018 Nov 1;29(13):1312-1332.            .

Gonzalez R, De la Rosa AJ, Rufini A, Rodríguez-Hernández A, Navarro-Villarán E, Marchal T, Pereira S, De la Mata M, Müller-Schilling M, Pascasio-Acevedo JM, Ferrer-Ríos MT, Gómez-Bravo MA, Padillo FJ, Muntané J. Role of TA and ΔN p63 and p73 isoforms on the regulation of cell death and tumor recurrence in patients with hepatocellular carcinoma submitted to liver transplantation. Plos One 2017 Mar 28;12(3):e0174326.

Navarro-Villarán E, Tinoco J, Jiménez G, Pereira S, Wang J, Aliseda S, Rodríguez-Hernández MA, González R, Marín-Gómez LM, Gómez-Bravo MA, Padillo FJ, Álamo-Martínez JM, Muntané J. Differential antitumoral properties and renal-associated tissue damage induced by Tacrolimus and mamalian target of rapamycin inhibitors in hepatocarcinoma: in vitro and in vivo studies. PLoS One 2016 Agosto 12;11(8):e0160979.

Urtasun R, Elizalde M, Azkona M, Latasa MU, García-Irigoyen O, Uriarte I, Fernández-Barrena MG, Vicent S, Alonso MM, Muntané J, Prieto J, Ávila MA, Berasain C. Splicing regulator SLU7 preserves survival of hepatocellular carcinoma cells and other solid tumors via oncogenic mir-17-92 cluster expression. Oncogene 2016 Septiembre 8;35(36):4719-4729.

Rodríguez-Hernández A, Navarro-Villarán E, González R, Pereira S, Soriano-De Castro LB, Sarrias-Giménez A, Barrera-Pulido L, Álamo-Martínez JM, Serrablo-Requejo A, Blanco-Fernández G, Nogales-Muñoz A, Gila-Bohórquez A, Pacheco D, Torres-Nieto MA, Serrano-Díaz-Canedo J, Suárez-Artacho G, Bernal-Bellido C, Marín-Gómez LM, Barcena JA, Gómez-Bravo MA, Padilla CA, Padillo FJ, Muntané J. Regulation of cell death receptor S-nitrosylation and apoptotic signaling by Sorafenib in hepatoblastoma cells. Redox Biol. 2015 Diciembre;6:174-182.

Madejón A, Sheldon J, Francisco-Recuero I, Perales C, Domínguez-Beato M, Lasa M, Sánchez-Perez I, Muntané J, Domingo E, García-Samaniego J, Sánchez-Pacheco A.  Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivity. J Hepatol. 2015 Agosto;63(2):312-319.

González-Rubio S, López-Sánchez L, Muñoz-Castañeda J, Linares CI, Aguilar-Melero P, Rodríguez-Perálvarez M, Sánchez-Sánchez R, Fernández-Álvarez A, Casado M, Montero-Álvarez JL, Rodríguez-Ariza A, Muntané J, de la Mata M, Ferrín G. GCDCA down-regulates gene expression by increasing Sp2 binding to the NOS-3 promoter in an oxidative stress dependent manner. Biochem Pharmacol. 2015 Julio 1;96(1):39-51.

Castaño D, Larequi E, Belza I, Astudillo AM, Martínez-Ansó E, Balsinde J, Argemi JM, Aragon T, Moreno-Aliaga MJ, Muntane J, Prieto J, Bustos M. Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving. AMPK activation. J Hepatol 2014 Mayo;60(5):1017-1025.

Vaquero J, Monte MJ, Dominguez M, Muntané J, Marin JJ. Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoformss and the bile acid pool composition. Biochemical Pharmacology 2013 Octubre 1;86(7):926-939.

González R, Ferrín G, Aguilar-melero P, Ranchal I, Linares CI, Bello RI, De la Mata M, Gogvadze V, Bárcena JA, Álamo JM, Orrenius S, Padillo J, Zhivotovsky B, Muntané J. Targeting hepatoma using NO donor strategies. Antioxid. Redox Signal. 2013 Febrero 10;18(5):491-506.

Aguilar-Melero P, Ferrín G, Muntané J. Effects of nitric oxide synthase-3 overepxresion on post-translational modifications and cell survival in HepG2. Journal of Proteomics 2012 Enero 4;75(3): 740-755.